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There is a Legacy version here.

PFS StandardSpider VenomItem 5

Alchemical Consumable Injury Poison 
Source Player Core 2 pg. 294, GM Core pg. 250 2.0
Price 25 gp
Usage held in 2 hands; Bulk L
Activate [two-actions] (manipulate)
This spider venom erodes a target's defenses.

Saving Throw DC 22 Fortitude; Maximum Duration 6 rounds; Stage 1 1d10 poison damage and sickened 1 (1 round); Stage 2 1d12 poison damage, clumsy 1, and sickened 2 (1 round); Stage 3 2d6 poison damage, clumsy 2, and sickened 3 (1 round)