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Alchemical Poisons

Source Core Rulebook pg. 550
Alchemical poisons are potent toxins distilled or extracted from natural sources and made either stronger or easier to administer. Each poison’s stat block includes the Price and features for a single dose. Poison doses are typically kept in a vial or some other type of safe and secure container.

Applying alchemical poisons uses Interact actions. A poison typically requires one hand to pour into food or scatter in the air. Applying a poison to a weapon or another item requires two hands, with one hand holding the weapon or item. The Usage entry for a poison indicates the number of hands needed for a typical means of application, but the GM might determine that using poisons in other ways functions differently.

The full rules for how poisons and other afflictions work begin on page 457. A creature attempts the listed saving throw as soon as it’s exposed to the poison; on a failed save, the creature advances to stage 1 of the poison after any listed onset time elapses.

Some poisons have the virulent trait. This means the poison is harder to remove once it has taken effect; see Virulent Afflictions on page 458.

Click here for the full rules on Alchemical Poisons.

Name	Level	Price	Bulk
Arsenic	1	3 gp	L
Giant Centipede Venom	1	4 gp	L
Black Smear Poison	2	5 gp	L
Belladonna	2	5 gp	L
Black Adder Venom	2	6 gp	L
Lethargy Poison	2	7 gp	L
Blue Dragonfly Poison	3	7 gp	L
Cytillesh Oil	3	10 gp	L
Graveroot	3	10 gp	L
False Death	5	25 gp	L
Hunting Spider Venom	5	25 gp	L
Giant Scorpion Venom	6	40 gp	L
Isolation Draught	7	55 gp	L
Giant Wasp Venom	7	55 gp	L
Malyass Root Paste	7	55 gp	L
Addlebrain	7	58 gp	L
Nettleweed Residue	8	75 gp	L
Wyvern Poison	8	80 gp	L
Lich Dust	9	110 gp	L
Spider Root	9	110 gp	L
Wolfsbane	10	155 gp	L
Shadow Essence	10	160 gp	L
Blightburn Resin	11	225 gp	L
Mage Bane	12	325 gp	L
Slumber Wine	12	325 gp	L
Deathcap Powder	13	450 gp	L
Gorgon's Breath	13	475 gp	L
Purple Worm Venom	13	500 gp	L
Dragon Bile	15	925 gp	L
Mindfog Mist	15	1,000 gp	L
Weeping Midnight	16	1,400 gp	L
Nightmare Vapor	16	1,400 gp	L
Frenzy Oil	16	1,500 gp	L
Brimstone Fumes	16	1,500 gp	L
Hemlock	17	2,250 gp	L
King's Sleep	18	4,000 gp	L
Oblivion Essence	19	6,500 gp	L
Black Lotus Extract	19	6,500 gp	L
Tears of Death	20	12,000 gp	L
Nightmare Salt	20	14,000 gp	L

Archives of Nethys

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Alchemical Poisons