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Archives of Nethys

Archives of Nethys

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Alchemical Poisons

 Source Core Rulebook pg. 550 2.0
Alchemical poisons are potent toxins distilled or extracted from natural sources and made either stronger or easier to administer. Each poison's stat block includes the Price and features for a single dose. Poison doses are typically kept in a vial or some other type of safe and secure container.

Applying alchemical poisons uses Interact actions. A poison typically requires one hand to pour into food or scatter in the air. Applying a poison to a weapon or another item requires two hands, with one hand holding the weapon or item. The Usage entry for a poison indicates the number of hands needed for a typical means of application, but the GM might determine that using poisons in other ways functions differently.

The full rules for how poisons and other afflictions are located here. A creature attempts the listed saving throw as soon as it's exposed to the poison; on a failed save, the creature advances to stage 1 of the poison after any listed onset time elapses.

Some poisons have the virulent trait. This means the poison is harder to remove once it has taken effect; see Virulent Afflictions.

Divine Poisons

Poisons with the divine trait are infused with an element of divine power, elevating them to a magical state beyond what alchemy could normally achieve. These deadly concoctions provide magical side effects in addition to their usual debilitating properties. Normally crafted by followers of deities of poisons like Norgorber and Ydersius, these poisons are magic items. Their effects can't be dispelled by dispel magic.

Click here for the full rules on Alchemical Poisons.
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NamePFSSourceRarityTraitsCategorySubcategoryLevelPriceBulkSpoilers?
Arsenic PFS Standard Core Rulebook Common Alchemical, Consumable, Ingested, Poison Alchemical Items Alchemical Poisons 1 3 gp L —
Spear Frog Poison — Bestiary 2 Common Alchemical, Consumable, Injury, Poison Alchemical Items Alchemical Poisons 1 3 gp L —
Giant Centipede Venom PFS Standard Core Rulebook Common Alchemical, Consumable, Injury, Poison Alchemical Items Alchemical Poisons 1 4 gp L —
Belladonna PFS Standard Core Rulebook Common Alchemical, Consumable, Ingested, Poison Alchemical Items Alchemical Poisons 2 5 gp L —
Black Smear Poison PFS Restricted Bestiary Uncommon Alchemical, Consumable, Injury, Poison Alchemical Items Alchemical Poisons 2 5 gp L —
Black Adder Venom PFS Standard Core Rulebook Common Alchemical, Consumable, Injury, Poison Alchemical Items Alchemical Poisons 2 6 gp L —
Looter's Lethargy — Pathfinder #157 Uncommon Alchemical, Consumable, Contact, Poison Alchemical Items Alchemical Poisons 2 6 gp L Agents of Edgewatch
Toad Tears — Bestiary 2 Common Alchemical, Consumable, Ingested, Poison Alchemical Items Alchemical Poisons 2 6 gp L —
Lethargy Poison PFS Standard Core Rulebook Uncommon Alchemical, Consumable, Incapacitation, Injury, Poison, Sleep Alchemical Items Alchemical Poisons 2 7 gp L —
Yellow Musk Vial — Bestiary 2 Uncommon Alchemical, Consumable, Inhaled, Mental, Poison Alchemical Items Alchemical Poisons 2 7 gp L —
Blue Dragonfly Poison PFS Restricted Bestiary Uncommon Alchemical, Consumable, Ingested, Poison Alchemical Items Alchemical Poisons 3 7 gp L —
Cytillesh Oil PFS Standard Core Rulebook Common Alchemical, Consumable, Injury, Poison Alchemical Items Alchemical Poisons 3 10 gp L —
Graveroot PFS Standard Core Rulebook Common Alchemical, Consumable, Injury, Poison Alchemical Items Alchemical Poisons 3 10 gp L —
Violet Venom — Bestiary 2 Uncommon Alchemical, Consumable, Contact, Poison Alchemical Items Alchemical Poisons 3 12 gp L —
Leadenleg PFS Standard Advanced Player's Guide Common Alchemical, Consumable, Injury, Poison Alchemical Items Alchemical Poisons 4 15 gp L —
Stupor Poison PFS Limited Pathfinder #165 Uncommon Alchemical, Consumable, Incapacitation, Injury, Poison, Sleep Alchemical Items Alchemical Poisons 4 16 gp L Abomination Vaults
False Death PFS Limited Pathfinder #149 Uncommon Alchemical, Consumable, Ingested, Poison Alchemical Items Alchemical Poisons 5 25 gp L Age of Ashes
Hunting Spider Venom PFS Standard Core Rulebook Common Alchemical, Consumable, Injury, Poison Alchemical Items Alchemical Poisons 5 25 gp L —
Forgetful Ink — Pathfinder #169 Uncommon Alchemical, Consumable, Contact, Poison Alchemical Items Alchemical Poisons 6 32 gp L Strength of Thousands
Giant Scorpion Venom PFS Standard Core Rulebook Common Alchemical, Consumable, Injury, Poison Alchemical Items Alchemical Poisons 6 40 gp L —
Giant Wasp Venom PFS Standard Core Rulebook Common Alchemical, Consumable, Injury, Poison Alchemical Items Alchemical Poisons 7 55 gp L —
Isolation Draught PFS Limited Pathfinder #149 Uncommon Alchemical, Consumable, Ingested, Poison Alchemical Items Alchemical Poisons 7 55 gp L Age of Ashes
Malyass Root Paste PFS Standard Core Rulebook Common Alchemical, Consumable, Contact, Poison Alchemical Items Alchemical Poisons 7 55 gp L —
Addlebrain PFS Limited Pathfinder #147 Rare Alchemical, Consumable, Inhaled, Poison Alchemical Items Alchemical Poisons 7 58 gp L Age of Ashes
Sloughing Toxin PFS Limited Pathfinder #164 Rare Alchemical, Consumable, Injury, Poison Alchemical Items Alchemical Poisons 7 60 gp L Abomination Vaults
Knockout Dram — Pathfinder #157 Uncommon Alchemical, Consumable, Ingested, Poison Alchemical Items Alchemical Poisons 7 70 gp L Agents of Edgewatch
Nettleweed Residue PFS Standard Core Rulebook Common Alchemical, Consumable, Contact, Poison Alchemical Items Alchemical Poisons 8 75 gp L —
Wyvern Poison PFS Standard Core Rulebook Common Alchemical, Consumable, Injury, Poison Alchemical Items Alchemical Poisons 8 80 gp L —
Lich Dust PFS Standard Core Rulebook Common Alchemical, Consumable, Ingested, Poison Alchemical Items Alchemical Poisons 9 110 gp L —
Spider Root PFS Standard Core Rulebook Common Alchemical, Consumable, Contact, Poison Alchemical Items Alchemical Poisons 9 110 gp L —
Sight-Theft Grit — Pathfinder #160 Uncommon Consumable, Divine, Ingested, Poison Alchemical Items Alchemical Poisons 9 115 gp L Agents of Edgewatch
Wolfsbane PFS Standard Core Rulebook Common Alchemical, Consumable, Ingested, Poison Alchemical Items Alchemical Poisons 10 155 gp L —
Fearweed — Pathfinder #160 Uncommon Consumable, Contact, Divine, Poison Alchemical Items Alchemical Poisons 10 160 gp L Agents of Edgewatch
Shadow Essence PFS Standard Core Rulebook Common Alchemical, Consumable, Injury, Negative, Poison Alchemical Items Alchemical Poisons 10 160 gp L —
Honeyscent PFS Standard Legends Rare Alchemical, Consumable, Inhaled, Poison Alchemical Items Alchemical Poisons 10 180 gp L —
Blightburn Resin PFS Standard Core Rulebook Common Alchemical, Consumable, Contact, Poison Alchemical Items Alchemical Poisons 11 225 gp L —
Hunger Oil — Pathfinder #160 Uncommon Consumable, Contact, Divine, Poison Alchemical Items Alchemical Poisons 11 235 gp L Agents of Edgewatch
Mage Bane PFS Limited Pathfinder #149 Uncommon Alchemical, Consumable, Injury, Poison Alchemical Items Alchemical Poisons 12 325 gp L Age of Ashes
Slumber Wine PFS Standard Core Rulebook Common Alchemical, Consumable, Ingested, Poison, Sleep Alchemical Items Alchemical Poisons 12 325 gp L —
Spell-Eating Pitch — Pathfinder #160 Uncommon Consumable, Divine, Injury, Poison Alchemical Items Alchemical Poisons 12 325 gp L Agents of Edgewatch
Blackfinger Blight — Pathfinder #159 Rare Alchemical, Consumable, Contact, Poison, Virulent Alchemical Items Alchemical Poisons 12 350 gp L Agents of Edgewatch
Deathcap Powder PFS Standard Core Rulebook Common Alchemical, Consumable, Ingested, Poison Alchemical Items Alchemical Poisons 13 450 gp L —
Spectral Nightshade — Pathfinder #160 Uncommon Consumable, Divine, Ingested, Poison Alchemical Items Alchemical Poisons 13 450 gp L Agents of Edgewatch
Gorgon's Breath PFS Limited Pathfinder #149 Uncommon Alchemical, Consumable, Inhaled, Poison Alchemical Items Alchemical Poisons 13 475 gp L Age of Ashes
Daylight Vapor — Pathfinder #160 Uncommon Consumable, Divine, Inhaled, Poison Alchemical Items Alchemical Poisons 13 500 gp L Agents of Edgewatch
Purple Worm Venom PFS Standard Core Rulebook Common Alchemical, Consumable, Injury, Poison Alchemical Items Alchemical Poisons 13 500 gp L —
Death Knell Powder — Pathfinder #160 Uncommon Consumable, Divine, Injury, Poison Alchemical Items Alchemical Poisons 14 625 gp L Agents of Edgewatch
Liar's Demise — Pathfinder #160 Uncommon Consumable, Contact, Divine, Poison Alchemical Items Alchemical Poisons 14 650 gp L Agents of Edgewatch
Dragon Bile PFS Standard Core Rulebook Common Alchemical, Consumable, Contact, Poison Alchemical Items Alchemical Poisons 15 925 gp L —
Mindfog Mist PFS Standard Core Rulebook Common Alchemical, Consumable, Inhaled, Poison Alchemical Items Alchemical Poisons 15 1,000 gp L —
Lifeblight Residue — Pathfinder #160 Uncommon Consumable, Divine, Injury, Poison, Virulent Alchemical Items Alchemical Poisons 15 1,100 gp L Agents of Edgewatch
Nightmare Vapor PFS Standard Core Rulebook Common Alchemical, Consumable, Inhaled, Poison Alchemical Items Alchemical Poisons 16 1,400 gp L —
Weeping Midnight PFS Limited Pathfinder #149 Uncommon Alchemical, Consumable, Injury, Poison Alchemical Items Alchemical Poisons 16 1,400 gp L Age of Ashes
Cerulean Scourge PFS Standard Advanced Player's Guide Common Alchemical, Consumable, Injury, Poison Alchemical Items Alchemical Poisons 16 1,450 gp L —
Brimstone Fumes PFS Standard Core Rulebook Common Alchemical, Consumable, Evil, Inhaled, Poison Alchemical Items Alchemical Poisons 16 1,500 gp L —
Frenzy Oil PFS Limited Pathfinder #149 Uncommon Alchemical, Consumable, Contact, Poison Alchemical Items Alchemical Poisons 16 1,500 gp L Age of Ashes
Repulsion Resin — Pathfinder #160 Uncommon Consumable, Divine, Ingested, Poison Alchemical Items Alchemical Poisons 16 1,650 gp L Agents of Edgewatch
Hemlock PFS Standard Core Rulebook Common Alchemical, Consumable, Ingested, Poison Alchemical Items Alchemical Poisons 17 2,250 gp L —
King's Sleep PFS Standard Core Rulebook Common Alchemical, Consumable, Ingested, Poison, Virulent Alchemical Items Alchemical Poisons 18 4,000 gp L —
Black Lotus Extract PFS Standard Core Rulebook Common Alchemical, Consumable, Contact, Poison, Virulent Alchemical Items Alchemical Poisons 19 6,500 gp L —
Oblivion Essence PFS Limited Pathfinder #149 Uncommon Alchemical, Consumable, Injury, Poison Alchemical Items Alchemical Poisons 19 6,500 gp L Age of Ashes
Tears of Death PFS Standard Core Rulebook Common Alchemical, Consumable, Contact, Poison, Virulent Alchemical Items Alchemical Poisons 20 12,000 gp L —
Nightmare Salt PFS Limited Pathfinder #149 Rare Alchemical, Consumable, Ingested, Poison Alchemical Items Alchemical Poisons 20 14,000 gp L Age of Ashes
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