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Player Core / Chapter 8: Playing the Game / Damage Rolls / Step 4: Reduce Hit Points

Nonlethal Attacks

Source Player Core pg. 407 2.0
You can make a nonlethal attack to knock someone out instead of killing them (see Knocked Out and Dying). Weapons with the nonlethal trait (including fists) do this automatically. You take a –2 circumstance penalty to the attack roll when you make a nonlethal attack using a weapon or unarmed attack that doesn’t have the nonlethal trait. You also take this penalty when making a lethal attack using a nonlethal weapon. Spells and other effects with the nonlethal trait that reduce a creature to 0 Hit Points knock the creature out instead of killing them.