There is a Remastered version
here.

Serene Mutagen
Item 1+Legacy Content
Alchemical Consumable Elixir Mutagen Polymorph Source Core Rulebook pg. 549 4.0Usage held in 1 hand;
Bulk L
Activate [one-action] Interact
You gain inner serenity, focused on fine details and steeled against mental assaults, but you find violence off-putting.
Benefit You gain an item bonus to Will saves and Perception, Medicine, Nature, Religion, and Survival checks. This bonus improves when you attempt Will saves against mental effects.
Drawback You take a –1 penalty to attack rolls and save DCs of offensive spells, and a –1 penalty per damage die to all weapon, unarmed attack, and spell damage.
Serene Mutagen (Lesser)Item 1
Source Core Rulebook pg. 549 4.0Price 4 gp
The bonus is +1, or +2 vs. mental, and the duration is 1 minute.
Serene Mutagen (Moderate)Item 3
Source Core Rulebook pg. 549 4.0Price 12 gp
The bonus is +2, or +3 vs. mental, and the duration is 10 minutes.
Serene Mutagen (Greater)Item 11
Source Core Rulebook pg. 549 4.0Price 300 gp
The bonus is +3, or +4 vs. mental, and the duration is 1 hour. When you roll a success on a Will save against a mental effect, you get a critical success instead.
Serene Mutagen (Major)Item 17
Source Core Rulebook pg. 549 4.0Price 3,000 gp
The bonus is +4, and the duration is 1 hour. When you roll a success on a Will save against a mental effect, you get a critical success instead, and your critical failures on Will saves against mental effects become failures instead.